Microsoft Skype for Business gives users the option of having Skype for Business open upon start-up or waiting to open the Software at their discretion.  Users can change this option in Settings by doing the following:

  1. Open Microsoft Skype for Business
  2. Click the Setting's Gear icon
  3. Click the Personal tab.
  4. To keep Skype for Business from opening on start-up, uncheck the box that says “Automatically start the app when I log in to Windows” Then click OK.